|
Zoonotic form of cutaneous leishmaniasis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
MCP-1 and IL-10 were expressed at comparable levels in ZCL and SCL lesions.
|
30810524 |
2019 |
|
Yersinia infections
|
0.020 |
Biomarker
|
group |
BEFREE |
The relevance of LcrV-mediated immunosuppression for the pathogenicity of yersiniae became evident by experimental infection of mice; in contrast to wild-type mice, IL-10-/- mice were highly resistant against Yersinia infection, as shown by lower bacterial load in spleen and liver, absent abscess formation in these organs, and survival.
|
11801671 |
2002 |
|
Yersinia infections
|
0.020 |
AlteredExpression
|
group |
BEFREE |
Tissue levels of IL-10, as well as the inflammatory cytokines TNF-alpha, IL-6, and gamma interferon and the chemokine macrophage chemotactic protein 1, are similar in TLR2(+/+) and TLR2(-/-) mice during enteropathogenic Yersinia infection.
|
17420232 |
2007 |
|
Yellow Fever
|
0.010 |
Biomarker
|
disease |
BEFREE |
For this purpose, memory status of circulating T-cells (Naïve/early-effector/Central-Memory/Effector-Memory) and B-cells (Naïve/non-Classical-Memory/Classical-Memory) along with the cytokine profile (IFN/TNF/IL-5/IL-10) were monitored before-NV(day0) and at distinct time-points after 17DD-YF primary vaccination-PV(day30-45); PV(year1-9) and PV(year10-11).
|
29879134 |
2018 |
|
Xanthomatosis, Cerebrotendinous
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
However, imipenem combined with low-dose CTX significantly reduced IL-6 and IL-10 expression and significantly increased occludin expression compared with imipenem alone (P<0.05).
|
30186419 |
2018 |
|
X-Linked Lymphoproliferative Disorder
|
0.020 |
Biomarker
|
disease |
BEFREE |
Thus, insufficient IL-10 production may contribute to hypogammaglobulinemia in XLP.
|
15761493 |
2005 |
|
X-Linked Lymphoproliferative Disorder
|
0.020 |
Biomarker
|
disease |
BEFREE |
Intracellular IL-10, IL-21 and IL-4 reached higher values in XLP than N after 8 days.
|
21996454 |
2011 |
|
X-linked agammaglobulinemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
We found that XLA-DC normally differentiate from monocyte precursors and mature in response to lipopolysaccharide (LPS) as assessed by de novo expression of CD83, up-regulation of MHC class II, B7.1 and B7.2 molecules as well as interleukin (IL)-12 and IL-10 production.
|
12823285 |
2003 |
|
Wheezing
|
0.090 |
AlteredExpression
|
phenotype |
BEFREE |
Furthermore, wheezing children with MPP had a significantly higher level of IL-10 than children with MPP without wheezing (43.75±26.644 vs. 27.50±10.211 pg/ml, p=0.027).
|
28057814 |
2017 |
|
Wheezing
|
0.090 |
GeneticVariation
|
phenotype |
BEFREE |
We aimed to determine whether IL10 polymorphisms are associated with helminth infection and the risk of wheeze and allergy.
|
23273955 |
2013 |
|
Wheezing
|
0.090 |
GeneticVariation
|
phenotype |
BEFREE |
Regarding the clinical outcomes, reduced LPS-induced IL-10 responses at birth were associated with recurrent wheeze.
|
28089873 |
2017 |
|
Wheezing
|
0.090 |
Biomarker
|
phenotype |
BEFREE |
Interleukin-10 (IL-10) has been associated with wheezing and asthma in children and the genetic variation of the IL-10 cytokine production may be linked to post-bronchiolitis lung function.
|
26473365 |
2015 |
|
Wheezing
|
0.090 |
Biomarker
|
phenotype |
BEFREE |
IL10 family member genes IL19 and IL20 are associated with recurrent wheeze after respiratory syncytial virus bronchiolitis.
|
21814157 |
2011 |
|
Wheezing
|
0.090 |
GeneticVariation
|
phenotype |
BEFREE |
IL10 polymorphisms influence neonatal immune responses, atopic dermatitis, and wheeze at age 3 years.
|
23021880 |
2013 |
|
Wheezing
|
0.090 |
Biomarker
|
phenotype |
BEFREE |
We previously showed that airflow limitation during RSV LRTI as well as convalescent monocyte IL-10 production are associated with early wheezing.
|
17313976 |
2007 |
|
Wheezing
|
0.090 |
GeneticVariation
|
phenotype |
BEFREE |
IL-10 polymorphisms at rs1800871, rs1800872, rs1800890, and rs1800896 seem to be associated with elevated allergies and/or recurrent wheezing risk in later childhood, after early-life bronchiolitis.Pediatr Pulmonol.2017;52:14-20.
|
27228545 |
2017 |
|
Wheezing
|
0.090 |
Biomarker
|
phenotype |
BEFREE |
Wheeze was inversely associated with SWA-specific IFN-γ (P < .001) and IL-10 (P = .058), and SEA-specific IL-5 (P = .004).
|
29171863 |
2018 |
|
West Nile viral infection
|
0.010 |
Biomarker
|
disease |
BEFREE |
Consistent with an etiologic role of IL-10 in WNV pathogenesis, we find that WNV infection is markedly diminished in IL-10 deficient (IL-10(-/-)) mice, and pharmacologic blockade of IL-10 signaling by IL-10 neutralizing antibody increases survival of WNV-infected mice.
|
19816558 |
2009 |
|
West Nile Fever
|
0.010 |
Biomarker
|
disease |
BEFREE |
Moreover, CD4(+) T cells produce copious amounts of IL-10, and may be an important cellular source of IL-10 during WNV infection in vivo.
|
19816558 |
2009 |
|
Weight decreased
|
0.400 |
Therapeutic
|
phenotype |
CTD_human |
Effects of interleukin-4 or interleukin-10 gene therapy on trinitrobenzenesulfonic acid-induced murine colitis.
|
24314293 |
2013 |
|
Weight decreased
|
0.400 |
Biomarker
|
phenotype |
CTD_human |
Effects of interleukin-4 or interleukin-10 gene therapy on trinitrobenzenesulfonic acid-induced murine colitis.
|
24314293 |
2013 |
|
Weight decreased
|
0.400 |
Therapeutic
|
phenotype |
CTD_human |
Alterations in Enterohepatic Fgf15 Signaling and Changes in Bile Acid Composition Depend on Localization of Murine Intestinal Inflammation.
|
27580383 |
2016 |
|
Weight decreased
|
0.400 |
Biomarker
|
phenotype |
CTD_human |
Alterations in Enterohepatic Fgf15 Signaling and Changes in Bile Acid Composition Depend on Localization of Murine Intestinal Inflammation.
|
27580383 |
2016 |
|
Weight decreased
|
0.400 |
Biomarker
|
phenotype |
HPO |
|
|
|
|
Waldenstrom Macroglobulinemia
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
Rebound of IL-6 and IL-10 serum levels also accompanied disease progression in WM patients with acquired BTK<sup>Cys481</sup> mutations.
|
29496671 |
2018 |